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Quinta de Ventozelo was once farmed by Cistercian monks who inhabited the region in the Middle Age. The monks transformed local agriculture and began production of port wine. The first historical mention of Ventozelo dates from 1288, but around 1500, by assignment of the Cistercian Monastery of S. Pedro das Águias, the Estate came into the hands of the hidalgos of Casa do Poço from Lamego.
One of the largest and oldest of the Douro estates, it has passed through different hands down the centuries, each moulding and transforming it into what it is today.